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Advanced Reduced Serum Media

The Pricella® Advanced Reduced Serum Media, including Advanced MEM, RPMI-1640, DMEM, and DMEM/F12, are upgraded formulations designed to support mammalian cell culture with significantly reduced serum supplementation. By incorporating essential bioactive compounds that mimic serum components, these media allow 50% to 90% reduction in Fetal Bovine Serum (FBS) usage without compromising cell growth rates or morphology, maintaining a stable culture environment even under lower serum conditions.

Pricella® Advanced Reduced Serum Media are intended strictly for research purposes and are not suitable for diagnostic or therapeutic applications in humans or animals. Optimal FBS and supplementation concentrations should be adjusted for each specific cell line to achieve maximum serum reduction.

View All Advanced Reduced Serum Media

Reasons to buy


Lower Serum Use

Reduces serum needs with essential components, minimizing variability.


Cost Efficiency

Cuts serum costs by over 50% without sacrificing quality.


Seamless Compatibility

Works with most cells directly, no adaptation required.


Reliable Cell Growth

Supports normal growth and morphology with reduced serum.

Performance Comparison of Cell Lines in Advanced Reduced Serum Media Formulations

Figure 1: Growth comparison of multiple cell lines cultured in Advanced RPMI-1640 (PM153110) with 5% FBS versus RPMI-1640 (PM150110) with 10% FBS.

Figure 2: Comparison of L-929 cell growth in Pricella® Advanced MEM (PM153410) and Company A's Advanced MEM with 0.5-5% FBS.

Compared to standard RPMI-1640 with 10% FBS, Pricella® Advanced RPMI-1640 with 5% FBS supports similar or even superior growth in cell lines like Raji and PC-12, with no significant changes in cell morphology (Figure 1). For L-929 cells, Pricella® Advanced MEM with 0.5-5% FBS demonstrates comparable growth and morphology to Company A's Advanced MEM, indicating equivalent performance at reduced serum levels (Figure 2).

Pricella® Advanced Reduced Serum Media

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